Effects of dietary fatty acids on mitochondrial phospholipid
نویسنده
چکیده
Abbreviations: B2M, β-2-microglobulin; BACT, β-actin; BHT: butylated hydroxytoluene; 10 cDNA, complementary DNA; CL, cardiolipin; COX, cytochrome c oxidase complex; DHA, 11 docosahexaenoic acid; ETC, electron transport chain; FA, fatty acid; FAME, fatty acid methyl 12 esters; HP-TLC, high performance thin layer chromatography; LA, linoleic acid; LC-PUFA, 13 long chain polyunsaturated fatty acid;MIM, mitochondrial inner membrane; mtDNA, 14 mitochondrial DNA; MUFA, monounsaturated fatty acids; NAC, no-amplification control; 15 ND, NADH-coenzyme Q oxidoreductase complex; NTC, no-template control; OA, oleic acid; 16 PC, phosphatidylcholine, PE, phosphatidylethanolamine; PI, phosphatidylinositol; PIn, 17 peroxidation index; PL, phospholipid; PS, phosphatidylserine; PUFA, polyunsaturated fatty 18 acid;qPCR, quantitative PCR; RO, rapeseed oil; ROS, reactive oxygen species; SFA, 19 saturated fatty acids; SM, sphingomyelin; RT-PCR, real-time PCR; SEM, standar error of the 20 mean; SGR, specific growth rate; SOD, superoxide dismutase;TBARS, thiobarbituric acid 21 reactive substances; TBA, thiobarbituric acid; TCA, trichloroacetic acid; TLC, thin layer 22 chromatography; Tm, melting temperature. 23
منابع مشابه
Embryonic development and growth performances of an endangered fish species Nandus nandus: effects of dietary polyunsaturated fatty acids supplementation
The present study explored the embryonic and larval development of an endangered fish species Nandus nandus and resolved larval growth performances with the dietary supplementation of different types of lipids. Fertilized eggs were collected from fiber glass tanks immediately after spontaneous spawning of N. nandus, which were fed with a 1% phospholipid (squid meal) supplemented diet for 3 mont...
متن کاملDietary supplementation with docosahexaenoic acid, but not eicosapentaenoic acid, dramatically alters cardiac mitochondrial phospholipid fatty acid composition and prevents permeability transition.
Treatment with the omega-3 polyunsaturated fatty acids (PUFAs) docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) exerts cardioprotective effects, and suppresses Ca2+-induced opening of the mitochondrial permeability transition pore (MPTP). These effects are associated with increased DHA and EPA, and lower arachidonic acid (ARA) in cardiac phospholipids. While clinical studies suggest t...
متن کاملDietary saturated fat and docosahexaenoic acid differentially effect cardiac mitochondrial phospholipid fatty acyl composition and Ca2+ uptake, without altering permeability transition or left ventricular function
High saturated fat diets improve cardiac function and survival in rodent models of heart failure, which may be mediated by changes in mitochondrial function. Dietary supplementation with the n3-polyunsaturated fatty acid docosahexaenoic acid (DHA, 22:6n3) is also beneficial in heart failure and can affect mitochondrial function. Saturated fatty acids and DHA likely have opposing effects on mito...
متن کاملDietary saturated fat and docosahexaenoic acid differentially effect cardiac mitochondrial phospholipid fatty acyl composition and Ca uptake, without altering permeability transition or left ventricular function
High saturated fat diets improve cardiac function and survival in rodent models of heart failure, which may be mediated by changes in mitochondrial function. Dietary supplementation with the n3-polyunsaturated fatty acid docosahexaenoic acid (DHA, 22:6n3) is also beneficial in heart failure and can affect mitochondrial function. Saturated fatty acids and DHA likely have opposing effects on mito...
متن کاملEmbryonic development and growth performances of an endangered fish species Nandus nandus: effects of dietary polyunsaturated fatty acids supplementation
The present study explored the embryonic and larval development of an endangered fish species Nandus nandus and resolved larval growth performances with the dietary supplementation of different types of lipids. Fertilized eggs were collected from fiber glass tanks immediately after spontaneous spawning of N. nandus, which were fed with a 1% phospholipid (squid meal) supplemented diet for 3 mont...
متن کاملP3: Food and Behavior: Long Chain Poly Unsaturated Fatty Acids and Anxiety
The anecdote "we are what we eat" in line with the doctrine of Hypocrates in 400 BC “Let food be thy medicine and medicine thy food” are vividly portray the importance of daily regimen in human health and body well-functioning. There is a growing body of evidence that suggests the relative intake of specific nutrients can have a profound effect on physiology of individuals...
متن کامل